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Proteins 101

Background

Molecule
  • Group of 2+ atoms
  • Held together by chemical bonds
  • Neutral electrical charge
Chemical compound
  • Substance made of many identical molecules
  • Where molecules use atoms from 2+ elements
Chemical formula
The elements and quantities in a compound('s) molecule
Functional group
  • a group of atoms in a molecule
  • with independant chemical properties
Side chain
Chemical group attached to the "main chain" of a molecule
Amino acid
  • compound
  • containing functional groups:
    • amino (-NH2)
    • carboxyl (-COOH)
  • + side chain specific to each amino acid
How many naturally occurring amino acids are known?
~500
How many types of amino acid appear in the genetic code?
20
Peptide
molecule made of chain of ~2-50 amino acids
Polypeptide
molecule made of chain of ~50 amino acids
Residues
the amino acids within a chain

Proteins

Protein
molecule made of ~50+ amino acids, in 1+ chains
Primary protein structure
Sequence of amino acid residues
Secondary protein structure
3D form of local segments
Tertiary protein structure
Global 3D form ➡️ determines the protein's functions